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Head of Vectorology, Global Gene Therapy

Company: Takeda Pharmaceuticals International GmbH
Location: Cambridge
Posted on: February 20, 2021

Job Description:

The health and safety of our employees and candidates is very important to us. Due to the current situation related to the Coronavirus (COVID-19), we're leveraging our digital capabilities to ensure we can continue to recruit top talent at Takeda. As your application progresses, you may be asked to use one of our digital tools to help you through your recruitment journey. If so, one of our colleagues will explain how these tools will be used during the recruitment process. Thank you. *Please be aware of an Identity Theft Scheme targeting individuals seeking jobs with Takeda and other employers. See below or here for more info. Head of Vectorology, Global Gene Therapy Takeda fosters a collaborative and stimulating work environment filled with opportunity and the chance to make a difference in people's lives. It is a workplace driven by integrity, one of Takeda's long-held values that extends to both the patients we serve and our employees who develop and deliver medicines. Across our company, Takeda employees bring together diverse strengths that together create a stronger whole. As one of the world's leading biopharmaceutical companies, Takeda is committed to bringing Better Health and a Brighter future to people worldwide. We aspire to bring our leadership in translating science into life-changing medicines to the next level, in our core focus areas; oncology, gastroenterology, neuroscience, rare diseases, plasma-derived therapies, and vaccines. The Greater Boston Area is headquarters to many of our Global and US business units. We are a passionate team doing important work that impacts patients' lives. If you are driven to create better health and a brighter future, join us! Success What makes a successful member of our team? Check out the traits we're looking for and see if you have the right mix. Life at Takeda A Global Top Employer Recognized for our culture and way of working, we're one of only select companies to receive Top Global Employer -- status for 2021. Head of Vectorology, Global Gene Therapy Job ID R0028969 Date posted 01/25/2021 Location Cambridge, Massachusetts Are you looking for a patient-focused company that enables transformative technologies to address patients' needs while inspiring you and support your career? Takeda is a world-class organization where we combine our expertise in disease biology, modality technologies and drug development experience to develop gene therpies in a holistic approach. We are seeking a highly motivated leader with substantial experience in vector design and gene therapy drug development experience to join Takeda to advance our gene therapy research effort. Be empowered and join us as a Head of Vectorology in the Global Gene Therapy Research Team. Objectives: As one of the leaders of the Global Gene Therapy (GGT) Research Team, the Head of Vectorology will be responsible and accountable for leading a team of vectorologist that contributes to discovery research gene therapy (GT) projects in the research pipeline. The incumbent will lead the team to continue to establish collaborations across multiple line functions to progress GT projects in a highly matrixed manner. For Director:

  • Provide leadership to a team of vectorology leads and molecular biology specailists to deisgn vectors appropriate for gene therapy therapeutic development and technology advancement projects. Responsible and accountable for appropriate data interpretations of the results of studies conducted by self and team members.
  • Represent the Vectorology team as the GGT LT member. Ensure cross team collaboration within GGT to obtain required resources to enable efficient progression of GT projects.
  • Enable the Vectorology team members to cross collaborate within the GGT team, multiple Discovery Disease Units (DDUs), global research platforms, Pharm Sci and other departments.
  • Provide scientific and strategic input to therapeutic gene therapy projects and gain alignment with other critical line functions including but not limited to the DDUs and Pharm Sci.
  • Constantly oversees project progression, experimental prioritization and communicate effectively to GGT LT in a timely manner.
  • Ability to balance multiple projects under a demanding timeline while providing guidance to a team of scientists.
  • Advice project teams on experimental planning to ensure good quality readout can be obtained to drive go/no-go decisions.
  • Stay on top of the literature and industrial technical advancement to improve vectorology capabilities by identifying novel approaches and propose experimental plan to test the hypothesis with the internal team and by the utilization of CROs.
  • Accountable for the development of organizational culture and capabilities. Ability to balance multiple projects under a demanding timeline while fostering a culture of cohesion, team work and transparency.
  • Responsible for management of resourcing and budget planning for his/her area of focus and accountable for effectiveness and timelines of completion of project goals.
  • Follow compliance of documentation in electronic lab notebook and author scientific reports that supports internal documentation and regulatory submissions. For Director:
    • PhD degree in a scientific discipline with 12+ years experience with 7 years of industry experience required. Prior managerial experience required.
    • Previous experience successfully leading gene and/or cell therapy drug development team/matrix teams through internal governance transitions. Ability to have timeline management and budget planning.
    • 7 years of managerial experience with extensive matrix leadership experience required
    • Direct experience in the design and testing of gene expression cassette and regulatory elements with developability properties suitable for viral and non-viral gene therapy candidates. In-depth technical expertise in gene therapy development.
    • Excellent interpersonal communication skills for presentations ,day-to-day project team communications, problem solving and conflict resolution Proactive ability to look for internal and/or external resources to enable progression of programs
    • Data-driven, critical thinking, analytical and ability to interpret results with statistical approaches. Excellent written skills to generate and review critical documents and reports.
    • Proficient in various computer softwares such as Word, PowerPoint, Excel, Graphpad Prism, Snapgene (or equivalent DNA sequence analysis software) and Microsoft Project (or of equivalent timeline generation software/tools). As a global organization, availability to participate in early or late meetings/teleconferences. Check out where you could be
      working if you apply. Job Seekers: Protect yourself against identity theft Please be aware there are instances of identity thieves posting Takeda-branded jobs and posing as employees to steal personal information. They visit job-related websites and invite candidates to online chats. During the chat, they press job seekers to provide bank account information and Social Security numbers. Copyright 1995-2019 Takeda Pharmaceutical Company Limited. All rights reserved.

Keywords: Takeda Pharmaceuticals International GmbH, Cambridge , Head of Vectorology, Global Gene Therapy, Healthcare , Cambridge, Massachusetts

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