Analytics and Bioassay Lead, Global Gene Therapy

Company: Takeda Pharmaceuticals International GmbH
Location: Cambridge
Posted on: February 17, 2021

Job Description:

The health and safety of our employees and candidates is very important to us. Due to the current situation related to the Coronavirus (COVID-19), we're leveraging our digital capabilities to ensure we can continue to recruit top talent at Takeda. As your application progresses, you may be asked to use one of our digital tools to help you through your recruitment journey. If so, one of our colleagues will explain how these tools will be used during the recruitment process. Thank you. *Please be aware of an Identity Theft Scheme targeting individuals seeking jobs with Takeda and other employers. See below or here for more info. Analytics and Bioassay Lead, Global Gene Therapy Takeda fosters a collaborative and stimulating work environment filled with opportunity and the chance to make a difference in people's lives. It is a workplace driven by integrity, one of Takeda's long-held values that extends to both the patients we serve and our employees who develop and deliver medicines. Across our company, Takeda employees bring together diverse strengths that together create a stronger whole. As one of the world's leading biopharmaceutical companies, Takeda is committed to bringing Better Health and a Brighter future to people worldwide. We aspire to bring our leadership in translating science into life-changing medicines to the next level, in our core focus areas; oncology, gastroenterology, neuroscience, rare diseases, plasma-derived therapies, and vaccines. The Greater Boston Area is headquarters to many of our Global and US business units. We are a passionate team doing important work that impacts patients' lives. If you are driven to create better health and a brighter future, join us! Success What makes a successful member of our team? Check out the traits we're looking for and see if you have the right mix. Life at Takeda A Global Top Employer Recognized for our culture and way of working, we're one of only select companies to receive Top Global Employer -- status for 2021. Analytics and Bioassay Lead, Global Gene Therapy Job ID R0030080 Date posted 02/10/2021 Location Cambridge, Massachusetts By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Job Description: Are you looking for a patient-focused company that enables transformative technologies to address patients' needs while inspiring you and support your career? Takeda is a world-class organization where we combine our expertise in disease biology, modality technologies and drug development experience to develop gene therapies in a holistic approach. We are seeking a highly motivated leader with substantial experience in gene therapy drug development experience to join Takeda to advance our gene therapy research effort. Be empowered and join us as Gene Therapy Analytics and Bioassays Lead in the Global Gene Therapy Research Team. Objective: As an Analytics and Bioassay Lead in the Global Gene Therapy (GGT) Research Team, you will be empowered with driving Gene Therapy (GT) assay development to characterize viral and non-viral vectors. The candidate is expected to have strong hands-on technical experience of GT cell-based assays as well as characterization assays for viral and non-viral vectors. Accountabilities Coordinate with the Head of Analytics and Bioassay in GGT team to prioritize assay development and sample testing priorities. Partner with GGT co-leads in order to coordinate testing of in-process and study related materials. Performs characterization assays such as ELISA, Gyros, and other immunoassays. Performs cell-based assays as well as maintaining various types of mammalian cells in an asceptic manner. Independently design, conduct, analyze and present experimental data with minimal guidance from management. Develops analytical assays according to ICH guidelines and analyzes in-process/stability samples within timelines. Serves as the Analytics and Bioassay group lead on team projects. Follow compliance of documentation in electronic lab notebook and author scientific reports that supports internal documentation and regulatory submissions. Positive attitude with a strong focus on hands on lab work and attention to detail to generate reproducible results. Maintains familiarity with current analytical and bioassay methods used for characterizing viral and non-viral gene therapy vectors. Ability to maintain multiple projects and timelines. Technical/Functional (Line) Expertise Demonstrates broad technical program knowledge Acts as the recognized scientific resource on an aspect of a program Leadership Identifies, plans and executes novel scientific projects and may manage the work of others a direct or matrixed structure Decision-making and Autonomy Independently manages workload and expectations Scientifically independent May influence decision making within the department Interaction Conducts scientific presentations to internal audiences Receives high level instructions on all work, determines methods on new assignments, works closely with manager, may manage junior staff EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS:-- PhD degree in Biology, Cell Biology, Chemistry or a related field with 2+ years experience , or MS with 8+ years experience, or BS with 10+ years experience Expertise in gene therapy cell based analytical assay development for viral or non-viral gene therapy vectors. Prior experience developing an analytical assay using ELISA, MSD, or Gyros is a must. Familiar with PCR based assay, such as qPCR, RT-PCR and ddPCR is a plus. Familiar with ICH guidelines for the development of bioassays. Ability to adapt to new and fast paced environment and navigate uncertainties. Excellent written, communication and presentation skills. Familiar with Microsoft Word, Excel, Powerpoint, GraphPad Prism, and laboratory software. Check out where you could be
working if you apply. Job Seekers: Protect yourself against identity theft Please be aware there are instances of identity thieves posting Takeda-branded jobs and posing as employees to steal personal information. They visit job-related websites and invite candidates to online chats. During the chat, they press job seekers to provide bank account information and Social Security numbers. Copyright 1995-2019 Takeda Pharmaceutical Company Limited. All rights reserved.

Keywords: Takeda Pharmaceuticals International GmbH, Cambridge , Analytics and Bioassay Lead, Global Gene Therapy, Healthcare , Cambridge, Massachusetts