Scientific Director - Discovery Toxicology

Company: Bristol Myers Squibb
Location: Cambridge
Posted on: January 27, 2023

Job Description:

Working with Us
Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams rich in diversity. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

Nonclinical Research and Development (NCRD) is an integrated function with responsibility for characterizing nonclinical safety and disposition characteristics of the entire BMS Research and Development pipeline programs, with critical role from early discovery to submission of marketing authorization applications. - We utilize our deep expertise in toxicology/pathology, ADME, PK/PD, biopharmaceutics and Bioanalytics in all modalities (small and large molecules, cellular therapies and other novel modalities) to collaborate with peer R&D functions to identify and solve issues, discover high quality drug candidates, enable their clinical development and successful marketing authorizations across the globe.

Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You'll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

We are seeking an experienced, exceptional toxicologist who will work in a dynamic, multidisciplinary matrixed team within our Discovery Toxicology organization to generate, interpret and translate data from nonclinical studies. The successful candidate will lead the development and execution of mechanistic investigations and biomarker strategies for programs in a wide variety of therapeutic areas. - This individual will design experiments to provide a complete toxicological profile of compounds and lead biomarker efforts to inform advancement into early non-clinical development. Experience in the analysis of multi-dimensional data sets, a strong understanding of oncology and immunology are desirable.

Key Responsibilities:
Be the toxicology lead and engage cross-functional departmental teams to execute strategies to generate, analyze, and interpret data from non-clinical toxicology studies.

Identify, establish and oversee external collaborations with key opinion leaders, consortium and CROs to advance our understanding of toxicology.

Collaborate with Research Biology, Chemistry, Bioinformatics and other functions to create synergy in developing research approaches.

Basic Qualifications:
Bachelor's Degree and 15+ years of academic / industry experience OR

Master's Degree and 12+ years of academic / industry experience OR

PhD and 8+ years of academic / industry experience

PLUS
6 or more years of leadership experience

Preferred Qualifications:
PhD in Toxicology or a relevant discipline with a minimum of 5-10 years relevant experience in industry or related rigorous research environment.

Demonstrated expertise in toxicology or a closely related field

Strong experimental background and experience in hypothesis-driven biological/translational research with demonstrated ability to execute well-designed experiments.

Ability to integrate complex scientific ideas and generate testable hypotheses

Experience with generation and analysis genomic or multiplexed protein detection or other related emerging platforms is desirable.

Broad understanding of drug discovery and development in both early- and late-stage development and familiarity with regulatory approval process.

Comprehensive knowledge of animal and human biology and physiology, especially clinical and functional changes associated with toxicity and mechanism of action of disease or toxicity.

Effective written and oral communication skills and ability to manage multiple research activities.

Provides and accepts inputs on study design and data interpretation and fosters a spirit of teamwork.

Demonstrated ability to solve complex scientific problems and excellent organizational skills.

Must be a highly flexible, results oriented, independent self-starter who enjoys working in a fast-paced and dynamic environment.

#LI-Hybrid
If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as "Transforming patients' lives through science--- ", every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in an inclusive culture, promoting diversity in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol
Physical presence at the BMS worksite or physical presence in the field is a necessary job function of this role, which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and it enhances the Company culture.

COVID-19 Information
To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. -Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. -This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

BMS is dedicated to ensuring that people with disabilities can perform complex functions through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

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