Scientific Director - Discovery Toxicology
Company: Bristol Myers Squibb
Posted on: January 27, 2023
Working with Us
Challenging. Meaningful. Life-changing. Those aren't words that are
usually associated with a job. But working at Bristol Myers Squibb
is anything but usual. Here, uniquely interesting work happens
every day, in every department. From optimizing a production line
to the latest breakthroughs in cell therapy, this is work that
transforms the lives of patients, and the careers of those who do
it. You'll get the chance to grow and thrive through opportunities
uncommon in scale and scope, alongside high-achieving teams rich in
diversity. Take your career farther than you thought possible.
Bristol Myers Squibb recognizes the importance of balance and
flexibility in our work environment. We offer a wide variety of
competitive benefits, services and programs that provide our
employees with the resources to pursue their goals, both at work
and in their personal lives. Read more:
When you join BMS, you are joining a diverse, high-achieving team
united by a common mission.
Nonclinical Research and Development (NCRD) is an integrated
function with responsibility for characterizing nonclinical safety
and disposition characteristics of the entire BMS Research and
Development pipeline programs, with critical role from early
discovery to submission of marketing authorization applications. -
We utilize our deep expertise in toxicology/pathology, ADME, PK/PD,
biopharmaceutics and Bioanalytics in all modalities (small and
large molecules, cellular therapies and other novel modalities) to
collaborate with peer R&D functions to identify and solve
issues, discover high quality drug candidates, enable their
clinical development and successful marketing authorizations across
Here, you'll get the chance to grow and thrive through
opportunities that are uncommon in scale and scope. You'll pursue
innovative ideas while advancing professionally alongside some of
the brightest minds in biopharma.
We are seeking an experienced, exceptional toxicologist who will
work in a dynamic, multidisciplinary matrixed team within our
Discovery Toxicology organization to generate, interpret and
translate data from nonclinical studies. The successful candidate
will lead the development and execution of mechanistic
investigations and biomarker strategies for programs in a wide
variety of therapeutic areas. - This individual will design
experiments to provide a complete toxicological profile of
compounds and lead biomarker efforts to inform advancement into
early non-clinical development. Experience in the analysis of
multi-dimensional data sets, a strong understanding of oncology and
immunology are desirable.
Be the toxicology lead and engage cross-functional departmental
teams to execute strategies to generate, analyze, and interpret
data from non-clinical toxicology studies.
Identify, establish and oversee external collaborations with key
opinion leaders, consortium and CROs to advance our understanding
Collaborate with Research Biology, Chemistry, Bioinformatics and
other functions to create synergy in developing research
Bachelor's Degree and 15+ years of academic / industry experience
Master's Degree and 12+ years of academic / industry experience
PhD and 8+ years of academic / industry experience
6 or more years of leadership experience
PhD in Toxicology or a relevant discipline with a minimum of 5-10
years relevant experience in industry or related rigorous research
Demonstrated expertise in toxicology or a closely related field
Strong experimental background and experience in hypothesis-driven
biological/translational research with demonstrated ability to
execute well-designed experiments.
Ability to integrate complex scientific ideas and generate testable
Experience with generation and analysis genomic or multiplexed
protein detection or other related emerging platforms is
Broad understanding of drug discovery and development in both
early- and late-stage development and familiarity with regulatory
Comprehensive knowledge of animal and human biology and physiology,
especially clinical and functional changes associated with toxicity
and mechanism of action of disease or toxicity.
Effective written and oral communication skills and ability to
manage multiple research activities.
Provides and accepts inputs on study design and data interpretation
and fosters a spirit of teamwork.
Demonstrated ability to solve complex scientific problems and
excellent organizational skills.
Must be a highly flexible, results oriented, independent
self-starter who enjoys working in a fast-paced and dynamic
If you come across a role that intrigues you but doesn't perfectly
line up with your resume, we encourage you to apply anyway. You
could be one step away from work that will transform your life and
Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as "Transforming patients' lives
through science--- ", every BMS employee plays an integral role in
work that goes far beyond ordinary. Each of us is empowered to
apply our individual talents and unique perspectives in an
inclusive culture, promoting diversity in clinical trials, while
our shared values of passion, innovation, urgency, accountability,
inclusion and integrity bring out the highest potential of each of
Physical presence at the BMS worksite or physical presence in the
field is a necessary job function of this role, which the Company
deems critical to collaboration, innovation, productivity, employee
well-being and engagement, and it enhances the Company culture.
To protect the safety of our workforce, customers, patients and
communities, the policy of the Company requires all employees and
workers in the U.S. and Puerto Rico to be fully vaccinated against
COVID-19, unless they have received an exception based on an
approved request for a medical or religious reasonable
accommodation. -Therefore, all BMS applicants seeking a role
located in the U.S. and Puerto Rico must confirm that they have
already received or are willing to receive the full COVID-19
vaccination by their start date as a qualification of the role and
condition of employment. -This requirement is subject to state and
local law restrictions and may not be applicable to employees
working in certain jurisdictions such as Montana. This requirement
is also subject to discussions with collective bargaining
representatives in the U.S.
BMS is dedicated to ensuring that people with disabilities can
perform complex functions through a transparent recruitment
process, reasonable workplace adjustments and ongoing support in
their roles. Applicants can request an accommodation prior to
accepting a job offer. If you require reasonable accommodation in
completing this application, or in any part of the recruitment
process, direct your inquiries to email@example.com .
Visit careers.bms.com/ eeo -accessibility to access our complete
Equal Employment Opportunity statement.
BMS will consider for employment qualified applicants with arrest
and conviction records, pursuant to applicable laws in your
Any data processed in connection with role applications will be
treated in accordance with applicable data privacy policies and
Keywords: Bristol Myers Squibb, Cambridge , Scientific Director - Discovery Toxicology, Executive , Cambridge, Massachusetts
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