Scientific Director - Discovery Toxicology

Company: Bristol Myers Squibb
Location: Cambridge
Posted on: November 18, 2022

Job Description:

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference. We are seeking an experienced, exceptional toxicologist who will work in a dynamic, multidisciplinary matrixed team within our Discovery Toxicology organization to generate, interpret and translate data from nonclinical studies. The successful candidate will lead the development and execution of mechanistic investigations and biomarker strategies for programs in a wide variety of therapeutic areas. This individual will design experiments to provide a complete toxicological profile of compounds and lead biomarker efforts to inform advancement into early non-clinical development. Experience in the analysis of multi-dimensional data sets, a strong understanding of oncology and immunology are desirable. Key Responsibilities:

• Be the toxicology lead and engage cross-functional departmental teams to execute strategies to generate, analyze, and interpret data from non-clinical toxicology studies.
• Identify, establish and oversee external collaborations with key opinion leaders, consortium and CROs to advance our understanding of toxicology.
• Collaborate with Research Biology, Chemistry, Bioinformatics and other functions to create synergy in developing research approaches. Preferred Qualifications:
  • Demonstrated expertise in toxicology or a closely related field
  • Strong experimental background and experience in hypothesis-driven biological/translational research with demonstrated ability to execute well-designed experiments.
  • Ability to integrate complex scientific ideas and generate testable hypotheses
  • Experience with generation and analysis genomic or multiplexed protein detection or other related emerging platforms is desirable.
  • Broad understanding of drug discovery and development in both early- and late-stage development and familiarity with regulatory approval process. Requirements:
    • PhD in Toxicology or a relevant discipline with a minimum of 5-10 years relevant experience in industry or related rigorous research environment.
    • Comprehensive knowledge of animal and human biology and physiology, especially clinical and functional changes associated with toxicity and mechanism of action of disease or toxicity.
    • Effective written and oral communication skills and ability to manage multiple research activities.
    • Provides and accepts inputs on study design and data interpretation and fosters a spirit of teamwork.
    • Demonstrated ability to solve complex scientific problems and excellent organizational skills
    • Must be a highly flexible, results oriented, independent self-starter who enjoys working in a fast-paced and dynamic environment.Why You Should Apply:Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to . Visit to access our complete Equal Employment Opportunity statement.Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

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