Director, mRNA Therapeutics/Synthetic Biology 1265776
Company: Stratacuity: Proven Scientific Placement
Location: Cambridge
Posted on: June 21, 2022
Job Description:
Job Scope & Purpose:Our newest, emerging partner in the field of
mRNA is seeking a Director, mRNA Synthetic Biology to lead and
drive their proprietary platform. This team is developing the next
generation of mRNA therapies that has increased selectivity and
critical applications in oncology and immune-oncology. The ideal
candidate will have direct experience within mRNA and molecule
biology with enough exposure to computation and delivery teams to
help drive success company wide.Primary Job Responsibilities:
- Independently design, execute and analyze mRNA studies, lead
the team and guide the company's mRNA strategy and Design and
construct DNA templates for in vitro transcription
- Work closely with computational biology and LNP teams to
deliver on technical milestones
- Work with senior management to expand the company's R&D
team
- Stay up-to-date on pertinent literature and prepare technical
reports and white papers for internal use
- Assist in I.P. filings and manuscript preparations
- Manage CROs and collaborate with academic partners for external
preclinical studies
- Independently design and execute experiments to develop and
optimize processes for mRNA synthesis
- Contribute creatively and strategically to assay design,
development, and process optimization.Primary Job Requirements:
- Ph.D. or M.D., plus a minimum of 4 years (post-degree)
industrial experience conducting cutting-edge research in
Biological Engineering, Molecular Biology or related field
- Deep knowledge of synthetic biology and mRNA therapeutics
- Expertise in RNA vector design, plasmid engineering, in vitro
transcription, RNA purification, and transfection in mammalian
systems
- Advanced knowledge and significant experience with primer
design, DNA isolation, and DNA assembly, and seamless cloning
- Experience with diverse molecular biology and microbiology
techniques, including DNA/RNA analysis, DNA, RNA, protein
purification, western blot, PCR, qRT-PCR, ELISA.
- Experience with animal studies, mammalian cell culture, and
analysis of protein expression and gene reporter systems with
various techniques such as confocal microscopy, flow cytometry,
cell luminescence, imagine systems, and quantitative data
analysis.
- Experience with automation
- Experience with analytical techniques HPLC, MALDI-TOF MS,
LC-MS/MS, NMR a plusAbout Stratacuity:Whether you are seeking a
career change or simply interested in becoming part of our network,
you will appreciate the ethics guiding each Stratacuity team
member. We build lasting relationships with exceptional
biopharmaceutical talent and take great care to protect your
personal information. Upon receiving your inquiry, you may be
directly contacted by a Stratacuity team member to discuss your
career goals. We will not share your information with anyone
without your direct prior consent.PROVEN SCIENTIFIC
PLACEMENT---Stratacuity is an Equal Employment
Opportunity/Affirmative Action Employer. All qualified applicants
will receive consideration for employment without regard to race,
color, religion, sex, age, sexual orientation, gender identity,
national origin, disability, protected veteran status, or any other
characteristic protected by law. Stratacuity will consider
qualified applicants with criminal histories in a manner consistent
with the requirements of applicable law. If you have visited our
website in search of information on employment opportunities or to
apply for a position, and you require an accommodation in using our
website for a search or application, please contact us.
Keywords: Stratacuity: Proven Scientific Placement, Cambridge , Director, mRNA Therapeutics/Synthetic Biology 1265776, Executive , Cambridge, Massachusetts
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