Director, tRNA Biology 1268503
Company: Stratacuity: Proven Scientific Placement
Location: Cambridge
Posted on: June 19, 2022
Job Description:
Job Scope & Purpose:Our new and exclusive client just secured a
significant Series A financing to progress the development of tRNA.
They have a proprietary pipeline of precision protein-editing
therapies dedicated to improving patients' lives in a myriad of
different genetically defined diseases. This team is seeking a
Director, tRNA Biology to drive the progression of their
proprietary platform and help to build the internal group. A
successful candidate will have significant exposure in molecular
biology and has previously built and led an effective research
team.Primary Job Responsibilities:
- The successful candidate will work both independently and as
part of a collaborative team to design, plan and execute
experiments that support platform and therapeutic development.
- Design, establish and execute robust, high-quality biochemical
and cell-based assays to support lead selection and
optimization.
- Establish and perform primary and develop functional assays to
support hit-to-lead and lead optimization
- Lead development and execution of cell-based assays to assess
biological activity of oligonucleotide-based compounds
- Manage relationships with external research facilities
- Report results to scientific team and management in written and
oral presentationsPrimary Job Requirements:
- PhD in biology, cell biology, molecular biology, immunology or
a related discipline with 8-10 years of experience in biotech or
pharmaceutical company.
- Extensive hands-on experience in mammalian cell culture,
including primary cells
- Expertise in DNA/RNA/siRNA transfection in vitro and ideally in
vivo
- Expertise in CRISPR and viral vector delivery is a plus
- Strong expertise in flow cytometry, cell sorting,
immunofluorescence and immunohistochemistry
- In-depth knowledge in assay design, optimization, validation,
data analysis and interpretation.
- Hands-on knowledge of cellular and molecular biology
techniques, such as, but not limited to, western blot, ELISA, qPCR
and molecular cloning.
- Critical data analysis, attention to detail, and
troubleshooting abilities.
- Excellent communication, organization, and problem-solving
skills
- tRNA biology expertise is a significant plusAbout
Stratacuity:Whether you are seeking a career change or simply
interested in becoming part of our network, you will appreciate the
ethics guiding each Stratacuity team member. We build lasting
relationships with exceptional biopharmaceutical talent and take
great care to protect your personal information. Upon receiving
your inquiry, you may be directly contacted by a Stratacuity team
member to discuss your career goals. We will not share your
information with anyone without your direct prior consent.PROVEN
SCIENTIFIC PLACEMENT---Stratacuity is an Equal Employment
Opportunity/Affirmative Action Employer. All qualified applicants
will receive consideration for employment without regard to race,
color, religion, sex, age, sexual orientation, gender identity,
national origin, disability, protected veteran status, or any other
characteristic protected by law. Stratacuity will consider
qualified applicants with criminal histories in a manner consistent
with the requirements of applicable law. If you have visited our
website in search of information on employment opportunities or to
apply for a position, and you require an accommodation in using our
website for a search or application, please contact us.
Keywords: Stratacuity: Proven Scientific Placement, Cambridge , Director, tRNA Biology 1268503, Executive , Cambridge, Massachusetts
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