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Sr. Director, Inflammation and Immunology Rx creation and Translational Research

Company: EQRx, Inc.
Location: Cambridge
Posted on: May 16, 2022

Job Description:

Sr. Director, Inflammation and Immunology Rx creation and Translational Research Rx Creation Cambridge, Massachusetts, United, States Full-Time Across the healthcare continuum, there is a shared common concern regarding rising drug spend and drug pricing. EQRx's innovative business model addresses the profound need for a more collaborative approach across the ecosystem to solve the challenges of patient access to innovative medicine at radically lower prices. Kent Rogers Chief Customer Officer EQRx believes responsibility can be revolutionary. Want to make a difference while advancing your career? Come join a team that is working towards our bold mission of developing innovative medicines at radically low prices to help people get the medicines they need. What You'll Do You will play a critical and highly visible role at EQRx by providing strategic, scientific, and technical leadership to cross functional project teams engaged in the discovery and development of novel I&I medicines and will drive translational research in these therapeutic areas. You will oversee the development of detailed work plans to incorporate quantitative, objective end points into clinical studies to demonstrate target engagement, pharmacodynamic regulation of pathways of interest, modulation of pharmacologic mechanism and information to aid patient selection. You will conceive and execute translation strategies to support robust decision making on the developability of drug molecules for immune-inflammatory diseases, and to provide the link between early research and clinical studies. You will be working across multiple functional groups and stakeholders to develop the Immuno-inflammatory strategy and lead our efforts in translational sciences including in vitro and in vivo pharmacology, biomarker development and IND-enabling studies. You will work with the biomarker team to plan and execute a CDx strategy as appropriate, and also to identify and implement new technologies and assays needed to support biomarker assays. This role will contribute to and author relevant regulatory submission documents (pre-IND, IND, IB, BLA, etc.) and provide strategic guidance on regulatory interactions relating to nonclinical development of drugs in immune-inflammatory diseases. You will work cross functionally and manage relationships with internal and external stakeholders. This role will establish and maintain an understanding of current trends in drug development for immuno-inflammatory diseases. An important requirement for success in this position is the ability to identify and leverage cutting-edge technologies that can significantly impact clinical drug development decisions and timelines and bring value to patients and prescribers. You will represent the RX Creation function at internal scientific reviews and governance meetings, external forums, consortia and health authority interactions and build relationships & collaborate with scientific leaders, KOLs, academic partners, CROs, and health authorities. The Impact You Will Have This role will have the opportunity to work across a diverse range of projects within I&I. You will bring foundational scientific expertise and exceptional leadership to the Rx creation team at EQRx. We are an early-stage company, so this is a highly visible and impactful role in our fast-growing organization. We are on a critical mission to bring quality solutions to patients at a fraction of the price. This role will help us drive towards that pinnacle goal of truly putting patients first. Your Superpowers

  • You have a Ph.D. in Immunology with a minimum of 12+ years of relevant drug discovery and translational research experience in a biopharmaceutical organization.
  • You possess expert level knowledge in reverse translation in inflammation and immunology (I&) medical disorders.
  • You have solid experience in developing relevant in vitro and in vivo translational disease models and applying them to support the advancement of drug discovery projects.
  • You have a demonstrated track record in the identification and validation of translational biomarkers to support informed decisions in pre- and clinical settings.
  • You are a strategic thinker with outstanding scientific excellence and accomplishments in immunology and inflammation as demonstrated by successful IND filings, strong publication record, patents, and/or conference presentations.
  • You have experience in authoring non-clinical study reports and sections of regulatory documents.
  • You have a demonstrated track record of managing technical activities at external partners and/or CROs and analysis/interpretation of results to drive projects to IND filing and clinical PoC.
  • You can work well cross functionally with complex issues and creating direction in shifting priorities and ambiguity.
  • You are results oriented with breadth and depth in translational research and biopharmaceutical development to resolve complex problems.
  • You have proven experience in building a high performing team. You have the ability to recruit and develop top talent, motivate and empower a team, work cross-functionally, and delegate effectively.
  • You have excellent verbal and written communication skills.
  • You understand relationships are key and have strong interpersonal skills.
  • Teams love working with you and you are someone who takes pride in mentoring and supporting the careers of others.
  • You can thrive in a smaller company environment and love the pace of a true startup.
  • You're a team player who is willing to roll-up your sleeves and get the job done. Are you bold enough? Your work should matter and allow you the freedom to be 100% you. We spend too much time and effort in our career to not feel excited and proud about what we do and who we do it with. In other words, your career is too important for your next move to be just another job, so let's work together to change the world and bring affordable medicines to all patients. We aren't about a bunch of empty slogans on a wall or words on a coffee cup - you can find that in lots of places. We are a culture of individuals with diverse backgrounds and personalities. Your work should matter and allow you the freedom to be 100% you. We spend too much time and effort in our career to not feel excited and proud about what we do and who we do it with. In other words, your career is too important for your next move to be just another job, so let's work together to change the world and bring affordable medicines to all patients. We aren't about a bunch of empty slogans on a wall or words on a coffee cup - you can find that in lots of places. We are a culture of individuals with diverse backgrounds and personalities. The Disruptor Are you ready to make waves in the industry and change the tides?
    • EQuality Medicines: Equally good or better, innovative medicines
    • EQuitable Medicines: Making innovative medicines affordable
    • EQual Access: Sustainable, frictionless access for people to cutting-edge medicines We have a bold mission and are looking for equally bold people who want to join us and help make a difference in the world. If you want to grease the wheel we are definitely not for you. Want to build the wheel? We might be just what you are looking for. EQRx is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law. It's (mutually) beneficial . You're curious about what sets us apart from the rest. What do you get from working at EQRx? So, let's start big-working at EQRx means having the opportunity to change the world. By joining a team that's remaking medicine development from start to finish, you're going to enjoy the daily rush of throwing caution to the wind and doing things differently by:
      • Working with the smartest game-changers in the industry
      • Cutting down the red tape of "the way things are done"
      • Seeing and feeling the daily impact of your work
      • Growing as a professional and a person
      • Committing to neverending social responsibility And, yes-we also have a killer list of things that'll help you shine as part of the team. But to us, these are just table stakes.
        • 100% Medical, Dental, and Vision coverage
        • Flexible Spending Account
        • Health Reimbursement Account
        • Free snacks and drinks *As EQRx grows, please note that some of these are subject to change. Find Your Professional
          SuperpowerWhat's yours? Find the right job for your skills. Stay in the Loop Get Job Alerts Follow us on social. Stay connected on Twitter, LinkedIn, Instagram & Glassdoor.

Keywords: EQRx, Inc., Cambridge , Sr. Director, Inflammation and Immunology Rx creation and Translational Research, Executive , Cambridge, Massachusetts

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