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Sr. Director, Rare Diseases

Company: Moderna Therapeutics
Location: Cambridge
Posted on: April 6, 2021

Job Description:

We seek a talented, experienced and motivated Senior Director to assist in developing the preclinical data package to support the advancement of Moderna's mRNA technology platform and pipeline. The successful candidate will drive the preclinical in vitro and in vivo pharmacology effort to validate the potential of novel mRNA therapeutics in the Rare Diseases therapeutic area. The successful candidate will lead the biochemistry and cell biology efforts, design and execute experiments, supervise laboratory personnel, present results internally and externally and manage collaborations and CROs. He/She will collaborate with different functions within Moderna including Platform, Clinical, Regulatory, Legal, Commercial and Manufacturing. Experience in IND filing is required as the candidate will help programs moving into Development. Applicants should be outstanding team members and have extensive experience in project management. Experience in Rare Diseases and Metabolic Disorders required. The ability to effectively communicate across internal multi-disciplinary teams and with external partners is required. The candidate will need to manage multiple project in a fast-move and results-oriented environment. Here's What You'll Do: Manage multiple projects of moderate to large size and scope involving cross-functional collaboration within Discovery and across departments. Provide scientific expertise, guidance and strategy to successfully bring programs to Go/No Go decisions. Lead a team of biologists to develop, optimize, validate and execute biochemical and/or cellular assays to support drug discovery projects, including assay development, and running of assays for mRNA research Provide expert level guidance in designing and implementing cell biology, biochemistry and biomarker related studies for rare diseases Ability to manage and supervise scientists to meet project timelines and teach direct reports assay and trouble shooting skills Support programs up to IND filing collaborating with multiple functions within Moderna Develop and manage relationship with clients. Have good communication skills, especially be capable of communicating effectively to discuss project progress, interpret and present data to clients Lead external collaborations. Act as a scientific resource providing guidance and mentorship to colleagues. Here's What You'll Bring to the Table: A Ph.D. degree in Biochemistry, Molecular Biology, Cell Biology or Immunology with 15+ years of overall experience, with 5-10 years of experience specifically in drug discovery in pharmaceutical, biotech or CRO Solid background and training in his or her own field of study and in conducting research using the latest drug discovery technologies and advances in science Managerial capabilities and good knowledge and experience in biologics and track record of making contributions to advance therapeutics from concept to proof-of concept in-vivo into a clinical candidate Familiarity with animal models used in Rare Disease research Extensive hands on experience in setting up in vitro and ex vivo biochemical assays Familiarity with disease biomarkers Experience in drug discovery or translational research in a biotech setting Experience in IND filing required Here's What We'll Bring to the Table:

  • On-site subsidized cafeteria or catered lunches
  • Company-provided iPhone
  • Free parking, monthly subway pass or a subsidized commuter rail pass
  • Free annual corporate membership to Bluebikes
  • Highly competitive healthcare coverage including: medical offered through BCBS (HMO/PPO), dental, and vision offered through VSP
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • 16 weeks of 100% paid parental leave for all new parents
  • 16 weeks 100% paid family caregiver leave
  • 20 weeks 100% paid medical leave
  • Eligible for "Moderna Month" (one month paid sabbatical after five years of service and eligible for additional one month paid sabbatical every 3 years thereafter)
  • Adoption assistance and discounts to local childcare centers, as well as access to care.com
  • 401k (traditional and Roth offered) with 50% match on first 6% deferred. Match is vested immediately
  • A suite of Moderna paid insurance coverage, including: life insurance, short-term and long-term disability
  • Voluntary legal assistance plan
  • 15 days' vacation and 7 sick days per year, in addition to a discretionary winter shut down and 11 company paid holidays (includes 2 floating holidays) About Moderna: In 10 years since its inception, Moderna has transformed from a science research-stage company advancing programs in the promising-but-still-unproven field of messenger RNA (mRNA), to an enterprise with its first medicine having treated millions of people, a diverse clinical portfolio of vaccines and therapeutics across six modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for both clinical and commercial production at scale and at unprecedented speed. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use of one of the earliest and most-effective vaccines against the COVID-19 pandemic. Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and auto-immune diseases. Today, 24 development programs are underway across these therapeutic areas, with 13 programs having entered the clinic. Moderna has been named a top biopharmaceutical employer by Science for the past six years. To learn more, visit www.modernatx.com . Moderna is a smoke-free, alcohol-free and drug-free work environment. Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. #LI-KF1 - Posted 2 Days Ago Full time R3529 About Us Our Mission and Vision At Moderna we are pioneering the development of a new class of drugs made of messenger RNA (mRNA). This novel drug platform builds on the discovery that modified mRNA can direct the body's cellular machinery to produce nearly any protein of interest, from native proteins to antibodies and other entirely novel protein constructs that can have therapeutic activity inside and outside of cells. We have a clear mission to propel the field of mRNA science forward and deliver new medicines to patients and a unique vision for how to achieve this mission. Our Mission: To deliver on the promise of transformative messenger RNA (mRNA) science to bring new medicines to patients. Our Vision: To unlock the potential of mRNA by establishing an ecosystem of teams and partners that will work together to develop the broadest possible array of drugs, across diverse therapeutic areas and routes of administration, for serious diseases that are not treatable today. Third Party Staffing Agencies M oderna does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Moderna from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Moderna and do not obligate Moderna to pay fees if we hire from those resumes. Reasonable Accommodation Notice Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.Applicants with disabilities may be entitled to reasonable accommodation under the terms of the Americans with Disabilities Act and certain state or local laws. Please inform the company's personnel representative by calling 617-460-9346 or emailing humanresources@modernatx.com if you need assistance completing any forms or to otherwise participate in the application process.Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.

Keywords: Moderna Therapeutics, Cambridge , Sr. Director, Rare Diseases, Executive , Cambridge, Massachusetts

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