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Director, Translational Science

Company: Takeda Pharmaceuticals International GmbH
Location: Cambridge
Posted on: April 6, 2021

Job Description:

The health and safety of our employees and candidates is very important to us. Due to the current situation related to the Coronavirus (COVID-19), we're leveraging our digital capabilities to ensure we can continue to recruit top talent at Takeda. As your application progresses, you may be asked to use one of our digital tools to help you through your recruitment journey. If so, one of our colleagues will explain how these tools will be used during the recruitment process. Thank you. *Please be aware of an Identity Theft Scheme targeting individuals seeking jobs with Takeda and other employers. See below or here for more info. Takeda fosters a collaborative and stimulating work environment filled with opportunity and the chance to make a difference in people's lives. It is a workplace driven by integrity, one of Takeda's long-held values that extends to both the patients we serve and our employees who develop and deliver medicines. Across our company, Takeda employees bring together diverse strengths that together create a stronger whole. As one of the world's leading biopharmaceutical companies, Takeda is committed to bringing Better Health and a Brighter future to people worldwide. We aspire to bring our leadership in translating science into life-changing medicines to the next level, in our core focus areas; oncology, gastroenterology, neuroscience, rare diseases, plasma-derived therapies, and vaccines. The Greater Boston Area is headquarters to many of our Global and US business units. We are a passionate team doing important work that impacts patients' lives. If you are driven to create better health and a brighter future, join us! Success What makes a successful member of our team? Check out the traits we're looking for and see if you have the right mix. Life at Takeda A Global Top Employer Recognized for our culture and way of working, we're one of only select companies to receive Top Global Employer -- status for 2021. Job ID R0032830 Date posted 03/16/2021 Location Boston, Massachusetts By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use . I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Director, Translational Science PDT Are you looking for a patient-focused, innovation-driven company that will inspire you and empower you to shine? Join us as Director, Translational Science PDT in our Cambridge, MA Office. At Takeda, we are transforming the pharmaceutical industry through our R&D-driven market leadership and being a values-led company. To do this, we empower our people to realize their potential through life-changing work. Certified as a Global Top Employer, we offer stimulating careers, encourage innovation, and strive for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our global teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world. Here, you will be a vital contributor to our inspiring, bold mission. POSITION OBJECTIVES: The PDT BU R&D group is dedicated to bringing forward new therapeutic approaches based on plasma-derived therapies for patients with a broad spectrum of rare and complex diseases. Takeda believes there is tremendous potential to do more to meet patients' and health care providers' expectations with plasma-derived and plasma-oriented therapies for patients with autoimmune, inflammatory, gastrointestinal, hematologic, and other complex diseases. This is a new, fast growing R&D organization, and the incoming incumbent will have the ability to co-create the future vision and operating model for the team. The Director, Translational Science, PDT, is responsible for leading and driving new, innovative ideas supporting plasma-derived therapies alone or in combination with other modalities, focusing on improving the understanding the disease biology and clinical outcomes. The incumbent will work closely with various key stakeholders and represent translational research function in various program development teams and sub- teams. POSITION ACCOUNTABILITIES: The incumbent will be responsible for performing innovative translational research in the area of autoimmune, inflammatory and/or hematological diseases. The Translational Science Lead will be accountable for:

  • Partnering cross-functionally in the scientific planning and execution of collaborative projects to support both ongoing and novel programs.
  • Represent Translational Research function in cross-functional program teams to advance plasma derived protein therapeutics.
  • Evaluate and propose rationale for combinatorial, pathomechanism-driven therapies for complex chronic diseases in the focused disease areas
  • Design and manage outsourced research and non-clinical studies at CROs to generate Proof-of-Concept for ongoing and novel development programs
  • Partner with other scientific leaders and executives, both internal key stakeholders and external KOLs to develop a scientific roadmap and research strategy for programs.
  • Partner with Computational Biology, Medical Affairs, Commercial, Business Development, and others to influence, develop a patient centric strategy and develop cohort specific datasets to drive novel hypothesis
  • Inspire a culture of scientific innovation and cross-functional collaboration within the organization.
  • Present and interpret scientific data to internal and external stakeholders, at conferences, and in journal articles. DIMENSIONS AND ASPECTS Technical/Functional (Line) Expertise
    • Outstanding expertise and depth of knowledge within a scientific area
    • Keeps up with the up-to-date scientific advancement (e.g. competitive landscape, new technology, new research portfolio, and new partnership) Leadership
      • Plays a leading scientific role on project team(s), setting high standards for rigor of thought
      • Embraces and demonstrates a diversity and inclusion mindset and role models these behaviors for the organization. Decision-making and Autonomy
        • Independently manages workload and expectations
        • Scientifically independent
        • Scientific driver for research strategy that impacts group internally and outside area of function Interaction
          • Initiates and leads external interactions and collaborations
          • Frequent contact with internal and external personnel at various management levels
          • Determines methods on new assignments; makes strategic recommendations on projects EDUCATION, BEHAVIORAL COMPETENCIES AND SKILLS:
            • The incumbent must be comfortable with working in a fast-paced environment and comfortable with ambiguity
            • Must show examples of leadership and collaboration with multi-disciplinary cross-functional global development and strategy teams
            • Track record in rheumatology, clinical immunology, hematology, gastrointestinal disorders or hepatic diseases is required
            • Advanced degree (PhD or MD, ideally MD/PhD (or equivalent)) is required
            • 10+ years of experience in clinical or translational research environment with profound understanding of molecular path- mechanisms is required
            • The position requires experience in molecular understanding of clinical manifestations, therapeutic approaches and a deep knowledge of the current research paradigms.
            • Previous experience in clinical study support and expertise in translational research and development of clinical biomarker assays to facilitate clinical endpoints is preferred.
            • Successful track record of developing employees and team members is advantageous ADDITIONAL INFORMATION WHAT TAKEDA CAN OFFER YOU:
              • 401(k) with company match and Annual Retirement Contribution Plan
              • Tuition reimbursement and Company match of charitable contributions
              • Health & Wellness programs including onsite flu shots and health screenings
              • Generous time off for vacation and the option to purchase additional vacation days
              • Community Outreach Programs Empowering Our People to Shine Discover more at-- No Phone Calls or Recruiters Please. In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply. Check out where you could be
                working if you apply. Job Seekers: Protect yourself against identity theft Please be aware there are instances of identity thieves posting Takeda-branded jobs and posing as employees to steal personal information. They visit job-related websites and invite candidates to online chats. During the chat, they press job seekers to provide bank account information and Social Security numbers. Copyright 1995-2019 Takeda Pharmaceutical Company Limited. All rights reserved.

Keywords: Takeda Pharmaceuticals International GmbH, Cambridge , Director, Translational Science, Executive , Cambridge, Massachusetts

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