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Senior Director/Vice President, Molecular Biology and Cloning

Company: Voyager Therapeutics
Location: Cambridge
Posted on: February 24, 2021

Job Description:

Senior Director/Vice President, Molecular Biology and Cloning Senior Director/Vice President,--Molecular Biology and Cloning Reports To Chief Medical Officer & Head of R&D Location Cambridge, MA We are Voyager Therapeutics, a company compelled by curiosity and powered by persistence. We are the seekers who specialize in clinical-stage gene therapy, focused on developing life-changing treatments for severe neurological diseases. Voyager is committed to advancing the field of AAV gene therapy through innovation in vector engineering, capsid discovery, manufacturing, and the optimization of dosing and delivery to enable these novel therapies. Our wholly owned and partnered pipeline focuses on severe neurological diseases, such as Parkinson's disease, Huntington's disease, Friedreich's Ataxia and other areas where patient communities are currently underserved. We've been busy, but we've got so much more to discover - such is the life of a Voyager. If you are someone who thrives on finding the elusive answers to tough questions, come explore with us! Driven by desire to develop life-changing therapies for patients with high unmet medical needs, you will play a key role in progressing the company's molecular biology, cloning and vector engineering efforts to advance the company's scientific, clinical development and business priorities.You will lead the company's development of innovative approaches to AAV vectors for the potential treatment of severe neurological diseases. Lead a team of highly talented scientists responsible for constructing and producing novel AAV vector cargo and payloads for research and developing and optimizing them for therapeutic purposes using a variety of approaches. Responsibilities:

  • Define and execute the company's cargo and payload design and optimization strategy
  • Direct the Voyager's vector engineering and vector biology efforts
  • Lead the development and discovery of novel enhancements to AAV transgene design including transcriptional regulation and tissue/cell-specificity
  • Advance the science and technology around the next generation of therapeutic payloads and formats including vectorized antibodies
  • Work closely with the company's SAB, Advisors and the scientific community-at-large to advance the company's vector engineering endeavors
  • Be recognized both within and outside the organization as Voyager's subject matter expert in vector engineering
  • Foster and maintain a positive culture aligned with Voyager's core values of passion, pioneering, integrity and collaboration. Minimum Qualifications
    • PhD or MD/PhD in molecular biology, molecular genetics and/or protein engineering
    • 10+ years of experience in biopharmaceutical research, discovery, or development with a substantial amount of that in gene therapy; including 5+ years leading, nurturing and developing scientific teams
    • Established scientific and publication track record in innovation in molecular biology
    • Demonstrated success driving projects forward and executing successfully on corporate goals and managing resources
    • Commitment to a culture of scientific excellence, patient-centricity, urgency of purpose, transparency, and collaboration
    • Outstanding interpersonal skills and strong management experience leading teams
    • Excellent communication skills including oral and written presentations to internal and external stakeholders and senior management
    • Solution-focused mindset and a proven ability to build community, coalitions and develop strong partnerships across functions. Strongly Preferred
      • Established experience in AAV biology and/or gene regulation
      • Experience in Neuroscience RECRUITING & STAFFING AGENCIES: Voyager Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Voyager or its employees is strictly prohibited unless contacted directly by Voyager's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Voyager, and Voyager will not owe any referral or other fees with respect thereto. Are you legally authorized to work in the United States? --*
        -- Will you now or in the future require sponsorship for employment visa status (e.g., H-1B visa status)? --*
        -- If you answered 'Yes' to the previous question, what is the specific Visa and how long is your authorization to work? --*

Keywords: Voyager Therapeutics, Cambridge , Senior Director/Vice President, Molecular Biology and Cloning, Executive , Cambridge, Massachusetts

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