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Associate Director/Director, Translational Sciences

Company: THIRD ROCK VENTURES, LLC
Location: Cambridge
Posted on: February 17, 2021

Job Description:

Associate Director/Director, Translational Sciences at Faze Medicines Faze Medicines is seeking an experienced drug discovery scientist with deep knowledge evaluating therapeutic efficacy in rodent models for rare genetic diseases and CNS disorders. The candidate will also be responsible for defining and executing a biomarker discovery strategy and should adopt a highly collaborative approach to establish strong relationships with external partners and the internal drug discovery team. This is a unique opportunity to join an innovative start up biotech from inception to develop novel therapeutics to meet currently unmet medical needs. We view you as an important team member whose contributions will be critical to our success.-- Your contributions may include:

  • Collaborate with the FAZE team to define and execute a strategy to evaluate efficacy in relevant rodent models in neurodegenerative diseases
  • Design and supervise the execution of studies and fully collaborate with drug discovery team to reach critical decision points leading to nomination of development candidates
  • Develop a strategy to discover and validate biomarkers suitable for clinical development Requirements + Qualifications
    • 7-10 years of relevant work experience in biotech/ pharma
    • Experience in ALS, Parkinson's and/ or Myotonic Dystrophy desired
    • Experience employing molecular profiling approaches to develop pathway-dependent biomarkers suitable for use in clinical development
    • Experience collaborating with biologists and chemists to generate in vivo target validation data using genetic and pharmacological methods.
    • Multiple examples of supporting medicinal chemistry efforts to identify develop candidates
    • Prior experience and record of accomplishment functioning in cross functional teams and willingness to adopt a hands-on approach to deliver in a start-up biotech environment
    • Prior experience in successfully implementing, utilizing and leveraging outsourcing strategies
    • Significant expertise working across disease indications with specific focus on RGD and CNS.
    • Extensive know-how using biochemical, molecular and behavioral endpoints is essential
    • Solid understanding of drug metabolism, PD biomarkers and endpoint correlations required
    • Strong written, oral and public speaking communication skills Strong interpersonal and collaboration skills
    • Clear and effective verbal and written communication skills
    • A demonstrated ability to think logically and critically
    • Ability to successfully participate in a highly-creative and enthusiastic start-up environment
    • Exemplify a patient-first mentality, courage, integrity, drive, and respect for all team members-- We are an equal opportunity employer offering a competitive salary and benefits package. All applicants should be legally entitled to work for any employer in the U.S. Note to Employment Agencies:--Please do not forward any agency resumes. The company will not be responsible for any fees related to resumes that are unsolicited. 29 Newbury Street
      3rd Floor
      Boston, MA 02116
      P (617) 585-2000

Keywords: THIRD ROCK VENTURES, LLC, Cambridge , Associate Director/Director, Translational Sciences, Executive , Cambridge, Massachusetts

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