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Principal Scientist/Associate Director

Company: The American College of Radiation Oncology
Location: Cambridge
Posted on: January 13, 2021

Job Description:

  • Principal Scientist/Associate Director, Translational Medicines BM Principal Scientist/Associate Director, Translational Medicines Principal Scientist/Associate Director, Translational Medicines Cambridge, MA Requisition Number: TM20-901 At Blueprint Medicines, we are creating a blueprint for the future of healthcare. We are a leading company in the personalized medicine revolution by focusing on delivering new medicines that are targeted to the genetic driver of disease. We do this by leveraging our one-of-a-kind drug discovery platform to discover, develop and work to bring highly-selective kinase inhibitors to patients globally. This prolific scientific platform has enabled Blueprint Medicines to build a pipeline of novel therapies that span three distinct areas of medicine; genomically defined cancers, rare diseases and cancer immunotherapy. Responsibilities:
    • We are seeking an experienced Translational Lead scientist to support projects across the Blueprint portfolio, ranging from early discovery to clinical stage programs
    • This emerging leader will support projects from a translational perspective with a focus on heme-oncology indications, cancers with mutational drivers, and rare genetic diseases
    • Oversee and lead work both internal and external as needed to support development, outsourcing and validation of clinically relevant biomarker assays (e.g., pharmacodynamic, predictive, prognostic and safety biomarkers)
    • Ability to work and collaborate cross functionally with various team members
    • Ability to integrate complex exploratory biomarker data emerging from both non-clinical and early clinical studies to develop and or refine patient selection strategies. Advise and influence cross functional project teams on experimental design, data interpretation and analysis
    • Provide results of analyses to project teams, and external stakeholders
    • Contribute, as needed, to preparation of relevant sections of regulatory submissions such as INDs and NDAs
    • This role also includes the opportunity to grow into a leadership role in the Translational Medicine group Qualifications:
      • Advanced degree (Masters, Ph.D. or equivalent) with experience in cancer biology and translational medicine
      • 5+ years of industry experience with a background in heme-oncology research
      • In depth knowledge of cancer genomics is required
      • Ability to drive projects from discovery to early clinical development with a focus on biomarkers and translational research Capabilities:
        • Demonstrated application of expertise in discovery research through early clinical development specifically in the area of cancer genomics
        • Familiarity with engaging and managing external efforts with contract research organizations and academic collaborators
        • Familiarity with data management and visualization tools related to cancer genomics and ability to collaborate with computational biology to analyze complex genomic data sets emerging from pre-clinical and clinical trial data sets
        • A team player, who listens effectively, invites response and discussion and promotes creative problem solving
        • Excellent verbal and written communication skills and ability to work independently
        • Ability to embrace Blueprint's core values: Patients First, Thoughtfulness, Trust, Optimism and Urgency All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran. WHO WE ARE: Blueprint Medicines' mission is to dramatically improve the lives of patients with genomically defined diseases. Our singular focus is to use our deep understanding of the genetic blueprint of cancer and other diseases driven by the abnormal activation of kinases to craft highly selective medicines aimed at eradicating these diseases. We don't think in small steps. We think in giant leaps. We are driven by the pursuit of new ideas, new innovations, and new ways of thinking. We know that what each and every one of us does matters and that our success depends on our ability to work together. We believe we are at our best as a company when our employees are thriving and foster a culture that provides opportunities to grow and develop professionally, while also having fun. Job Information
          • Job ID: 55200449
          • Location:
            Cambridge, Massachusetts, United States
          • Position Title: Principal Scientist/Associate Director, Translational Medicines
          • Company Name: Blueprint Medicines
          • Job Function: Biology,
            Oncology,
            Scientist
          • Job Type: Full-Time
          • Job Duration: Indefinite
          • Min Education: Master's Degree
          • Min Experience: 5-7 Years
          • Required Travel: 0-10% Jobs You May Like Research Associate, Molecular Biology Kernal Biologics Cambridge, Massachusetts, United States Senior Computational Biologist/ Data Scientist,... Kernal Biologics Cambridge, Massachusetts, United States Director/Senior Principal Scientist,... Kernal Biologics Cambridge, Massachusetts, United States Director/Senior Principal Scientist, LNP (Lipid... 2001 6th Ave, Suite 2700 Seattle, Washington 98121 (206) 956-3650

Keywords: The American College of Radiation Oncology, Cambridge , Principal Scientist/Associate Director, Executive , Cambridge, Massachusetts

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