Medical Director, US Medical Affairs

Company: Association of Academic Physiatrists
Location: Cambridge
Posted on: January 10, 2021

Job Description:

• Medical Director, US Medical Affairs - Systemic Mastocytosis BM Medical Director, US Medical Affairs - Systemic Mastocytosis --Medical Director, US Medical Affairs- Systemic Mastocytosis Cambridge, MA Requisition Number: MEA20-904 At Blueprint Medicines, we are creating a blueprint for the future of healthcare. We are a leading company in the personalized medicine revolution by focusing on delivering new medicines that are targeted to the genetic driver of disease. We do this by leveraging our one-of-a-kind drug discovery platform to discover, develop and work to bring highly-selective kinase inhibitors to patients globally. This prolific scientific platform has enabled Blueprint Medicines to build a pipeline of novel therapies that span three distinct areas of medicine; genomically defined cancers, rare diseases and cancer immunotherapy. Job Summary: The Sr/ Medical Director, US Medical Affairs will be responsible for Medical Affairs leadership in the successful preparation and execution of a launch of avapritinib as well as subsequent lifecycle management activities in Systemic Mastocytosis. S/he will report to the Vice President, US Medical Affairs, and will play a key role in bringing a transformative therapy to patients in need. This role requires leadership capabilities within a matrixed environment as well as a commitment to "rolling up one's sleeves" to get the work done. Responsibilities:
  • Develop and execute a cross-functionally aligned strategic US Medical Affairs plan, inclusive of performance metrics, to ensure the successful launch of avapritinib and subsequent successful life cycle management in Systemic Mastocytosis (SM)
  • Work with the US MSL team to establish or strengthen professional relationships with the medical and scientific community and compliantly exchange scientific knowledge with global and regional thought leaders, including 1:1 interactions, congress engagements, and advisory boards
  • Contribute to the design and execution of Late-Stage (phase 4) Clinical Development and expanded access programs for avapritinib
  • Be a subject matter expert, sharing knowledge and providing informed recommendations to other functions as needed. In particular, collaborate with the Commercial and Clinical organization to ensure external-facing materials and presentations are scientifically rigorous and clinically meaningful
  • Work with the internal teams to develop key messages regarding disease state, MOA, target product profile, and molecular diagnostics
  • Support the development and execution of a medical/scientific communication strategy for avapritinib in SM including a strategic, cross-functionally aligned post-hoc analysis data plan
  • Assess scientific/medical and educational needs across a variety of external stakeholders and subsequently develop the US strategic direction for support of ISTs and CME activities, including chairing relevant review committees
  • Directly or indirectly support team interactions with US health payers to answer any questions about medical or clinical research topics and supporting future inclusion of avapritinib in their policies
  • Collaborate internally with clinical and regulatory departments to support the planning, execution, and management of clinical trial activities, including ensuring that appropriate institutions and academic centers have opportunities to participate in Blueprint's clinical programs.
  • Support the MSL teams in the US to provide expertise, materials, and support as they engage with the broader HCP community.
  • Remain on the forefront of the relevant science and competitive landscapes Qualifications and Capabilities:
    • MD, PharmD or PhD with Oncology, Allergy/Immunology, or rare disease experience is required; a minimum of 7 years of medical affairs or clinical research experience within the pharmaceutical industry, CRO health-related consulting company, or biomedical/clinical experience within academia (or a combination of aforementioned)
    • Launch experience is critical, and experience launching the first compound in a novel disease is preferred
    • Ability to think innovatively about medical affairs strategy and accurately anticipate future consequences and trends
    • Demonstrated ability to lead by example and model collaborative behavior by soliciting opinions, coupled with the ability to make key decisions and be effective in getting the team behind the decisions
    • Excellent written and verbal communication skills
    • Experience conducting formal presentations to Senior Management and external opinion leaders
    • Strong analytical skills, especially with regard to understanding and interpreting scientific and clinical research and literature, are essential
    • Demonstrated self-starter and team player with strong interpersonal skills
    • Adept, nimble, energetic and comfortable in a fast-paced, dynamic and collaborative environment
    • Capable of taking a hands-on approach and willing to "roll up one's sleeves" All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran. WHO WE ARE: Blueprint Medicines' mission is to dramatically improve the lives of patients with genomically defined diseases. Our singular focus is to use our deep understanding of the genetic blueprint of cancer and other diseases driven by the abnormal activation of kinases to craft highly selective medicines aimed at eradicating these diseases. We don't think in small steps. We think in giant leaps. We are driven by the pursuit of new ideas, new innovations, and new ways of thinking. We know that what each and every one of us does matters and that our success depends on our ability to work together. We believe we are at our best as a company when our employees are thriving and foster a culture that provides opportunities to grow and develop professionally, while also having fun. Job Information
      • Job ID: 55305061
      • Location:
        Cambridge, Massachusetts, United States
      • Position Title: Medical Director, US Medical Affairs - Systemic Mastocytosis
      • Company Name: Blueprint Medicines
      • Job Function: Medical Affairs
      • Job Type: Full-Time
      • Job Duration: Indefinite
      • Min Education: Ph.D.
      • Min Experience: 7-10 Years Jobs You May Like AP Vice President, Head of EMEA Medical Affairs -... Acceleron Pharma Cambridge, Massachusetts, United States AP Director, Evidence Strategy, Global Medical... Acceleron Pharma Cambridge, Massachusetts, United States AP Senior Medical Director, Pulmonary, Global Medical... 10461 Mill Run Circle, Suite 730 Owings Mills, Maryland 21117 (410) 712-7120

Keywords: Association of Academic Physiatrists, Cambridge , Medical Director, US Medical Affairs, Executive , Cambridge, Massachusetts