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Director/Senior Director, Protein Sciences

Company: Civetta Therapeutics
Location: Cambridge
Posted on: September 15, 2020

Job Description:

Location: US-MA-Cambridge - US-MA-CambridgeID: 2020-1347# of Openings : 1Category: Research & DevelopmentAddress: 10 Wilson RoadOverview

Deerfield Management is an investment management firm committed to improving healthcare through investment, information and philanthropy. We have just launched a new company called Civetta Therapeutics located in Cambridge, MA that was founded by William Sellers (Broad Institute and Dana-Farber Cancer Institute) and Eric Fischer (Dana Farber Cancer Institute and Harvard Medical School). We are looking to engage a high-quality team of researchers to advance new medicines through small molecule intervention targeting propeller domains with the goal of developing important therapeutics for cancer and other indications. If you are a talented life sciences professional that can bring significant energy, passion and talent to the team, we welcome the opportunity to consider you for a position in this exciting, new company committed to thorough, mechanistically-driven science.


We are seeking an accomplished leader (at the Director to Senior Director level) to propel our protein sciences, building world-class capabilities in structural biology, biochemistry, gene-to-structure and protein expression. This position represents a leadership role in Civetta and will help to shape our scientific strategy, discovery biology vision, and corporate success.

Key Responsibilities

  • Help define and contribute to Civetta Therapeutic strategic goals and thinking around how best to collect and harness deep structural and mechanistic knowledge of propeller protein complexes to enable drug discovery across the class
  • Provide strategic leadership and expertise in protein expression and purification, structural characterization and structure-based drug design for beta-propeller proteins
  • Help build and guide the structural biology, protein sciences, and protein production teams, including a broad gene to structure pipeline and enablement of specific drug discovery programs
  • Contribute to development and implementation of strategies for target ID, target validation, hit finding and project execution using protein sciences (biochemistry, biophysics, structural biology, and proteomics)
  • Manage internal and external resources to enable world class protein science capabilities
  • Responsible for maintaining strong interface across disciplines working closely with medicinal chemistry, cell and molecular biology, and project teams


    • Ph.D. in Structural Biology, Biochemistry or related field with post-doc and 10+ years of drug discovery, team building and leadership experience
    • Demonstrated track record of drug discovery contributions and achievements evidenced in strong publication and presentation record, patents, and contributions to clinical stage programs
    • Excellent project management and organizational skills
    • Ability to mentor team members and contribute to strategy and vision of Civetta
    • Integrity, collaboration, energy and drive

      William Sellers is a core institute member of the Broad Institute of MIT and Harvard, a faculty member at Harvard Medical School, and faculty member and senior advisor to the president for experimental therapeutics at the Dana-Farber Cancer Institute.

      Eric Fischer is an Associate Professor in the Department of Biological Chemistry and Molecular Pharmacology at Harvard Medical School and an Independent Investigator, Dana-Farber Cancer Institute.

      Civetta Therapeutics provides equal employment opportunities (EEO) to all employees and applicants for employment without regard to religion, race, creed, color, sex, sexual orientation, alienage or citizenship status, national origin, age, marital status, pregnancy, disability, veteran or military status, predisposing genetic characteristics or any other characteristic protected by applicable federal, state or local law.


      #LI-DNI PI123540257

Keywords: Civetta Therapeutics, Cambridge , Director/Senior Director, Protein Sciences, Executive , Cambridge, Massachusetts

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