Lab Automation Engineer (Senior Associate Scientist, Neuroscience)

Company: Bristol Myers Squibb
Location: Cambridge
Posted on: November 24, 2022

Job Description:

At Bristol Myers Squibb, we are inspired by a single vision - transforming patients' lives through science. -In oncology, hematology, immunology and cardiovascular disease - and one of the most diverse and promising pipelines in the industry - each of our passionate colleagues contribute to innovations that drive meaningful change. We bring a human touch to every treatment we pioneer. Join us and make a difference.

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Neuroscience TRC is committed to development of transformational therapeutics for patients with neurodegenerative and neuromuscular diseases. We have built a network of external partnerships across multiple treatment modalities (small molecules, biologics and RNA targeting) that leverage our leadership in protein homeostasis and inflammation to attach neurological diseases. Internal research focuses on protein homeostasis by direct and ligand directed degradation, neuroinflammation and remyelination.

Areas of interest include, but are not limited to, the following approaches:
Disease modifying therapies for neurodegenerative, neuro-inflammatory and neuromuscular diseases; CNS targets that modulate protein homeostasis, protein clearance, inflammation and reduce or eliminate toxic protein production; Emerging technologies (RNA, DNA targeting, gene regulation, editing and replacement, vector optimization) that when matched to underlying disease genetics can deliver a precision medicine portfolio with a high probability of success to address unmet medical needs; Targets in orphan/rare neurological and neuromuscular diseases. AI/ML in target identification and neurology drug discovery; Translational tools and technologies such as digital neuroimaging and fluid biomarkers to track neurodegenerative diseases; Novel blood brain-barrier delivery technologies.

Here, you'll get the chance to grow and thrive through opportunities that are uncommon in scale and scope. You'll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

Position Responsibilities:
In the role as a Lab Automation Engineer (Senior Associate Scientist) within the Neuroscience TRC, the ideal candidate will:
Work with scientists to develop, optimize and implement automated workflows for iPSC maintenance, differentiation and maintenance of differentiated neurons

Work with scientists to develop, optimize and implement automated workflows for disease modelling, target identification and therapeutic profiling

Perform lab automation operations including protocol design, error recovery, point-teaching etc.

Train scientists on software tools and provide guidance on protocol design, editing, order scheduling and run execution in Cellario and Instinct V

Assist scientists with operation of automation platform, providing training and error-recovery support as needed

Explore and evaluate new technologies (automation, liquid handling, imagers and plate readers etc.) relevant to the needs of the group

Manage equipment scheduling, service contracts and regular equipment preventative maintenance

Perform and record QC tests of platform instruments such as liquid handlers and plate readers

Experience =

Basic Qualifications:
Bachelor's Degree
4+ years of academic and / or industry experience

Or
Master's Degree
2+ years of academic and / or industry experience

Preferred Qualifications:
Strong understanding of object-oriented programming

Experience working with service engineers to troubleshoot and maximize system uptime

Knowledgeable in instrument qualification processes.

Experience with lab automation scheduling software and robotic systems such as HighRes Cellario, Hamilton's Venus and Instinct V

Experience with liquid handling platforms such as Hamilton Microlab Vantage/STAR, HighRes Prime, Tecan Fluent etc)

Fast learner, adaptable and able to work effectively in a cross functional team environment

Additional good to have qualifications:
Experience with cell culture and routine molecular biology techniques

Hands-on experience applying lab automation to support screening or stem cell related workflows

BMSNEURO
#LI-Onsite
Around the world, we are passionate about making an impact on the lives of patients with serious diseases. Empowered to apply our individual talents and diverse perspectives in an inclusive culture, our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives.

Physical presence at the BMS worksite or physical presence in the field is an essential job function of this role which the Company deems critical to collaboration, innovation, productivity, employee well-being and engagement, and enhances the Company culture.

To protect the safety of our workforce, customers, patients and communities, the policy of the Company requires all employees and workers in the U.S. and Puerto Rico to be fully vaccinated against COVID-19, unless they have received an exception based on an approved request for a medical or religious reasonable accommodation. - Therefore, all BMS applicants seeking a role located in the U.S. and Puerto Rico must confirm that they have already received or are willing to receive the full COVID-19 vaccination by their start date as a qualification of the role and condition of employment. - This requirement is subject to state and local law restrictions and may not be applicable to employees working in certain jurisdictions such as Montana. This requirement is also subject to discussions with collective bargaining representatives in the U.S.

Our company is committed to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace adjustments and ongoing support in their roles. Applicants can request an approval of accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application or if you are applying to a role based in the U.S. or Puerto Rico and you believe that you are unable to receive a COVID-19 vaccine due to a medical condition or sincerely held religious belief, during or any part of the recruitment process, please direct your inquiries to adastaffingsupport@bms.com . Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Keywords: Bristol Myers Squibb, Cambridge , Lab Automation Engineer (Senior Associate Scientist, Neuroscience), Engineering , Cambridge, Massachusetts