Process Development Engineer
Company: CRISPR Therapeutics
Location: Cambridge
Posted on: February 25, 2021
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Job Description:
Job SummaryAs part of the Regenerative Medicine Group, we are
seeking a Engineer II/Engineer III to join an exciting,
fast-growing and well-financed company. Successful candidates will
be integral in developing stem cell-derived therapies for
regenerative medicine. The role will be responsible for development
of cell therapy production platforms and will participate in
development of advanced cell processing and culture systems.
Successful candidates will have strong process development/scale-up
skills for expansion and differentiation of pluripotent stem cells
in bioreactors. The position requires enthusiasm, passion,
self-motivation, attention to detail, and a desire to create novel
therapies for patients.Responsibilities* Proactive approach to work
and entrepreneurial spirit are key.* Independently execute
bioreactor stem cell culture experiments. * Support establishing
cellular process parameters and process scale-up activities. *
Culture of human pluripotent stem cells including maintenance,
expansion, * Perform and analyze in vitro cellular assays such as
cell counts, flow cytometry and imaging.* Apply DOE/QBD principals
to process development and process optimization.* Maintain clear
and complete experimental records. * Support drafting and revising
protocols and SOPs and regulatory sections and fillings (i.e.
IND).Minimum Qualifications* M.S. in Chemical/Biochemical
Engineering or related discipline with minimum 1 year of relevant
industrial work; or BS in Chemical/Biochemical Engineering or
related discipline and 3+ years of relevant experience.* Experience
working with cell processing devices and bioreactors is very
helpful.* Experience with mammalian cell culture. * Process
development experience in a bio-pharmaceutical setting working with
interdisciplinary and cross-cultural teams.* Ability to communicate
effectively with a diverse range of scientists and engineers.*
Ability to work independently as well as part of a results-oriented
research team.* Highly organized with significant attention to
detail.Preferred Qualifications* M.S. in Chemical/Biochemical
Engineering or related discipline with 2+ years of relevant
industrial work.* Extensive experience with operation of cell
culture bioreactor systems ideal.* Experience developing processes
for early phase clinical products.* Experience with Design of
Experiments (DOE) for process optimization. * Experience with
pluripotent stem cell culture.CRISPR Therapeutics, Inc. is
committed to equal employment opportunity and non-discrimination
for all employees and qualified applicants without regard to a
person's race, color, gender, age, religion, national origin,
ancestry, disability, veteran status, genetic information, sexual
orientation or any characteristic protected under applicable law.To
view our Privacy Statement, please click the following link:
http://www.crisprtx.com/about-us/privacy-policy
Keywords: CRISPR Therapeutics, Cambridge , Process Development Engineer, Engineering , Cambridge, Massachusetts
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